TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation.

Cui, Junqing; Pazdziorko, Stephen; Miyashiro, Joy S; Thakker, Paresh; Pelker, Jeffrey W; Declercq, Charlene; Jiao, Aiping; Gunn, Jason; Mason, Lawrence; Leonard, John P; Williams, Cara M M; Marusic, Suzana

Cui, Junqing; Pazdziorko, Stephen; Miyashiro, Joy S; Thakker, Paresh; Pelker, Jeffrey W; Declercq, Charlene; Jiao, Aiping; Gunn, Jason; Mason, Lawrence; Leonard, John P; Williams, Cara M M; Marusic, Suzana.

Affiliation

Cui J; Wyeth Research, Cambridge, MA 02140, USA. jcui@wyeth.com

J Allergy Clin Immunol ; 115(2): 309-15, 2005 Feb.

Article in En | MEDLINE | ID: mdl-15696086

Subject(s)

Bronchial Hyperreactivity/physiopathology; Bronchitis/pathology; Neutrophils/pathology; Th1 Cells/immunology; Adoptive Transfer; Animals; Bronchial Hyperreactivity/immunology; Bronchial Hyperreactivity/metabolism; Cytokines/genetics; Dexamethasone/pharmacology; Glucocorticoids/pharmacology; Interleukin-13/metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucus/metabolism; Ovalbumin/pharmacology; RNA, Messenger/metabolism; Receptors, Interleukin-8A/deficiency; Severity of Illness Index; Th2 Cells/immunology

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Database: MEDLINE Main subject: Bronchitis / Bronchial Hyperreactivity / Th1 Cells / Neutrophils Limits: Animals Language: En Journal: J Allergy Clin Immunol Year: 2005 Type: Article Affiliation country: United States

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