The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.

Charrel-Dennis, Marie; Terrazzini, Nadia; McBride, Jeffrey D; Kaye, Paul; Martensen, Pia M; Justesen, Just; Berger, Peter; Lapthorn, Adrian; Kelly, Charles; Roitt, Ivan M; Delves, Peter J; Lund, Torben

Charrel-Dennis, Marie; Terrazzini, Nadia; McBride, Jeffrey D; Kaye, Paul; Martensen, Pia M; Justesen, Just; Berger, Peter; Lapthorn, Adrian; Kelly, Charles; Roitt, Ivan M; Delves, Peter J; Lund, Torben.

Affiliation

Charrel-Dennis M; Department of Immunology and Molecular Pathology, University College London, 46 Cleveland Street, London W1T 4JF, United Kingdom.

Mol Endocrinol ; 19(7): 1803-11, 2005 Jul.

Article in En | MEDLINE | ID: mdl-15718290

Subject(s)

Chorionic Gonadotropin, beta Subunit, Human/genetics; Chorionic Gonadotropin, beta Subunit, Human/immunology; Amino Acid Substitution/genetics; Amino Acid Substitution/immunology; Animals; Antibodies/blood; Antibodies, Monoclonal/immunology; Arginine/genetics; Chorionic Gonadotropin, beta Subunit, Human/chemistry; Cross Reactions/immunology; Female; Glutamic Acid/genetics; Humans; Immunization; Luteinizing Hormone/immunology; Mice; Mice, Inbred BALB C; Mutation; Peptides/genetics; Peptides/immunology; Protein Conformation

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Database: MEDLINE Main subject: Chorionic Gonadotropin, beta Subunit, Human Limits: Animals / Female / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2005 Type: Article Affiliation country: United kingdom

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