Quantitative determination of alkylated quaternary amines and their n-hydroxylated metabolites in an enzyme incubation matrix by liquid chromatography electrospray ionization mass spectrometry. | Biomed Chromatogr;19(8): 579-85, 2005 Oct. | MEDLINE

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Quantitative determination of alkylated quaternary amines and their n-hydroxylated metabolites in an enzyme incubation matrix by liquid chromatography electrospray ionization mass spectrometry.

Holmes, Victoria E; Shaw, P Nicholas; Ortori, Catharine A; Barrett, David A.

Affiliation

Holmes VE; Centre for Analytical Bioscience, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK.

Biomed Chromatogr ; 19(8): 579-85, 2005 Oct.

Article in En | MEDLINE | ID: mdl-15803452

Subject(s)

Amines/analysis; Cytochrome P-450 Enzyme System/metabolism; Spectrometry, Mass, Electrospray Ionization/methods; Alkylation; Hydrolysis; Reference Standards

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Database: MEDLINE Main subject: Spectrometry, Mass, Electrospray Ionization / Cytochrome P-450 Enzyme System / Amines Language: En Journal: Biomed Chromatogr Year: 2005 Type: Article Affiliation country: United kingdom

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Database: MEDLINE Main subject: Spectrometry, Mass, Electrospray Ionization / Cytochrome P-450 Enzyme System / Amines Language: En Journal: Biomed Chromatogr Year: 2005 Type: Article Affiliation country: United kingdom