In vitro partition of irinotecan (CPT-11) in human volunteer blood: the influence of concentration, gender and smoking.

Dumez, Herlinde; Guetens, Gunther; De Boeck, Gert; Highley, Martin S; de Bruijn, Ernst A; van Oosterom, Allan T; Maes, Robert A A

Dumez, Herlinde; Guetens, Gunther; De Boeck, Gert; Highley, Martin S; de Bruijn, Ernst A; van Oosterom, Allan T; Maes, Robert A A.

Affiliation

Dumez H; Department of Clinical Oncology/Laboratory of Experimental Oncology, UZ Gasthuisberg, Leuven, Belgium. Herlinde.Dumez@uz.kuleuven.ac.be

Anticancer Drugs ; 16(8): 893-5, 2005 Sep.

Article in En | MEDLINE | ID: mdl-16096439

Subject(s)

Antineoplastic Agents, Phytogenic/blood; Antineoplastic Agents, Phytogenic/pharmacokinetics; Camptothecin/analogs & derivatives; Erythrocytes/metabolism; Smoking/adverse effects; Camptothecin/blood; Camptothecin/pharmacokinetics; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Irinotecan; Male; Sex Distribution; Spectrometry, Fluorescence; Topoisomerase I Inhibitors

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Database: MEDLINE Main subject: Camptothecin / Smoking / Erythrocytes / Antineoplastic Agents, Phytogenic Limits: Female / Humans / Male Language: En Journal: Anticancer Drugs Journal subject: ANTINEOPLASICOS Year: 2005 Type: Article Affiliation country: Belgium

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