Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients.

Weekers, Laurent; Bouhanick, Béatrice; Hadjadj, Samy; Gallois, Yves; Roussel, Ronen; Pean, Franck; Ankotche, Amos; Chatellier, Gilles; Alhenc-Gelas, François; Lefebvre, Pierre J; Marre, Michel

Weekers, Laurent; Bouhanick, Béatrice; Hadjadj, Samy; Gallois, Yves; Roussel, Ronen; Pean, Franck; Ankotche, Amos; Chatellier, Gilles; Alhenc-Gelas, François; Lefebvre, Pierre J; Marre, Michel.

Affiliation

Weekers L; Department of Medicine, Centre Hospitalier Universitaire du Sart Tilman, Liege, Belgium.

Diabetes ; 54(10): 2961-7, 2005 Oct.

Article in En | MEDLINE | ID: mdl-16186399

Subject(s)

Angiotensin-Converting Enzyme Inhibitors/therapeutic use; Diabetes Mellitus, Type 1/enzymology; Hyperglycemia/enzymology; Kidney/drug effects; Peptidyl-Dipeptidase A/genetics; Polymorphism, Genetic; Adult; Albuminuria; Aldosterone/blood; Blood Pressure; Diabetes Mellitus, Type 1/drug therapy; Diabetes Mellitus, Type 1/physiopathology; Female; Gene Deletion; Genotype; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney/blood supply; Male; Mutagenesis, Insertional; Peptidyl-Dipeptidase A/blood; Ramipril/therapeutic use; Renin/blood

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Database: MEDLINE Main subject: Polymorphism, Genetic / Angiotensin-Converting Enzyme Inhibitors / Peptidyl-Dipeptidase A / Diabetes Mellitus, Type 1 / Hyperglycemia / Kidney Type of study: Clinical_trials Limits: Adult / Female / Humans / Male Language: En Journal: Diabetes Year: 2005 Type: Article Affiliation country: Belgium

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