Conformationally constrained CCK4 analogues incorporating IBTM and BTD beta-turn mimetics.

Martín-Martínez, Mercedes; De la Figuera, Natalia; Latorre, Miriam; García-López, M Teresa; Cenarruzabeitia, Edurne; Del Río, Joaquín; González-Muñiz, Rosario

Martín-Martínez, Mercedes; De la Figuera, Natalia; Latorre, Miriam; García-López, M Teresa; Cenarruzabeitia, Edurne; Del Río, Joaquín; González-Muñiz, Rosario.

Affiliation

Martín-Martínez M; Instituto de Química Médica (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain.

J Med Chem ; 48(24): 7667-74, 2005 Dec 01.

Article in En | MEDLINE | ID: mdl-16302807

Subject(s)

Bridged Bicyclo Compounds, Heterocyclic/chemistry; Dipeptides/chemistry; Indoles/chemistry; Tetragastrin/analogs & derivatives; Tetragastrin/chemical synthesis; Amylases/metabolism; Animals; Cerebral Cortex/metabolism; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Mimicry; Pancreas/drug effects; Pancreas/metabolism; Protein Structure, Secondary; Radioligand Assay; Rats; Receptor, Cholecystokinin A/antagonists & inhibitors; Structure-Activity Relationship; Tetragastrin/chemistry; Tetragastrin/pharmacology

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Database: MEDLINE Main subject: Tetragastrin / Bridged Bicyclo Compounds, Heterocyclic / Dipeptides / Indoles Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2005 Type: Article Affiliation country: Spain

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