Targeting the TCR: T-cell receptor and peptide-specific tolerance-based strategies for restoring self-tolerance in CNS autoimmune disease.

Kohm, Adam P; Turley, Danielle M; Miller, Stephen D

Kohm, Adam P; Turley, Danielle M; Miller, Stephen D.

Affiliation

Kohm AP; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Medical School, Chicago, IL 60611, USA.

Int Rev Immunol ; 24(5-6): 361-92, 2005.

Article in En | MEDLINE | ID: mdl-16318987

Subject(s)

Autoimmune Diseases of the Nervous System/therapy; Immunotherapy/methods; Peptides/immunology; Receptors, Antigen, T-Cell/immunology; Self Tolerance/immunology; Animals; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/therapeutic use; Autoimmune Diseases of the Nervous System/immunology; CD3 Complex/immunology; Clinical Trials as Topic; Cytokines/immunology; Humans; Immunosuppression Therapy/methods; Models, Immunological; Multiple Sclerosis/immunology; Multiple Sclerosis/therapy; Peptides/therapeutic use; Receptors, Interleukin-2/immunology; T-Lymphocyte Subsets/immunology; T-Lymphocytes, Regulatory/immunology

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Database: MEDLINE Main subject: Peptides / Receptors, Antigen, T-Cell / Self Tolerance / Autoimmune Diseases of the Nervous System / Immunotherapy Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Int Rev Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2005 Type: Article Affiliation country: United States

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