Grg1 acts as a lung-specific oncogene in a transgenic mouse model.

Allen, Thaddeus; van Tuyl, Minke; Iyengar, Pratibha; Jothy, Serge; Post, Martin; Tsao, Ming-Sound; Lobe, Corrinne G

Allen, Thaddeus; van Tuyl, Minke; Iyengar, Pratibha; Jothy, Serge; Post, Martin; Tsao, Ming-Sound; Lobe, Corrinne G.

Affiliation

Allen T; Molecular and Cellular Biology Division, Sunnybrook and Women's College Health Science Centre S-236, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5.

Cancer Res ; 66(3): 1294-301, 2006 Feb 01.

Article in En | MEDLINE | ID: mdl-16452182

Subject(s)

Adenocarcinoma/genetics; Lung Neoplasms/genetics; Oncogenes; Repressor Proteins/genetics; Adenocarcinoma/metabolism; Animals; Co-Repressor Proteins; ErbB Receptors/biosynthesis; ErbB Receptors/genetics; Genetic Vectors/genetics; Humans; Lung Neoplasms/metabolism; Mice; Mice, Transgenic; NIH 3T3 Cells; Receptor, ErbB-2/biosynthesis; Receptor, ErbB-2/genetics; Repressor Proteins/biosynthesis; Signal Transduction; Tumor Suppressor Protein p53/metabolism; Up-Regulation; ras Proteins/metabolism

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Database: MEDLINE Main subject: Oncogenes / Repressor Proteins / Adenocarcinoma / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2006 Type: Article

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