1,2,3,4,6-penta-O-galloyl-beta-D-glucose up-regulates heme oxygenase-1 expression by stimulating Nrf2 nuclear translocation in an extracellular signal-regulated kinase-dependent manner in HepG2 cells.

Pae, Hyun-Ock; Oh, Gi-Su; Jeong, Sun-Oh; Jeong, Gil-Saeng; Lee, Bok-Soo; Choi, Byung-Min; Lee, Ho-Sub; Chung, Hun-Taeg

Pae, Hyun-Ock; Oh, Gi-Su; Jeong, Sun-Oh; Jeong, Gil-Saeng; Lee, Bok-Soo; Choi, Byung-Min; Lee, Ho-Sub; Chung, Hun-Taeg.

Affiliation

Pae HO; Medicinal Resources Research Institute, Wonkwang University, Iksan-Shi, Chonbug, 570-749, Republic of Korea.

World J Gastroenterol ; 12(2): 214-21, 2006 Jan 14.

Article in En | MEDLINE | ID: mdl-16482620

Subject(s)

Cell Nucleus/metabolism; Extracellular Signal-Regulated MAP Kinases/physiology; Gene Expression Regulation, Enzymologic/drug effects; Heme Oxygenase-1/genetics; Hydrolyzable Tannins/pharmacology; NF-E2-Related Factor 2/metabolism; Active Transport, Cell Nucleus; Cells, Cultured; Cytoprotection; Enzyme Induction/drug effects; Heme Oxygenase-1/analysis; Humans; MAP Kinase Signaling System; Oxidative Stress; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation, Enzymologic / Cell Nucleus / Hydrolyzable Tannins / Extracellular Signal-Regulated MAP Kinases / Heme Oxygenase-1 / NF-E2-Related Factor 2 Limits: Humans Language: En Journal: World J Gastroenterol Journal subject: GASTROENTEROLOGIA Year: 2006 Type: Article

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