[Prophylactic thyroidectomy in children who are carriers of a multiple endocrine neoplasia type 2 mutation: description of 20 cases and recommendations based on the literature].

de Groot, J W B; Links, T P; Rouwe, C W; van der Wal, J E; Hofstra, R M W; Plukker, J T M

[Prophylactic thyroidectomy in children who are carriers of a multiple endocrine neoplasia type 2 mutation: description of 20 cases and recommendations based on the literature]. / Profylactische thyreoïdectomie bij kinderen die drager zijn van een mutatie van multipele endocriene neoplasie type 2: beschrijving van 20 casussen en aanbevelingen op grond van de literatuur.

de Groot, J W B; Links, T P; Rouwe, C W; van der Wal, J E; Hofstra, R M W; Plukker, J T M.

Affiliation

de Groot JW; Afd. Heelkunde en Endocrinologie, Universitair Medisch Centrum Groningen, Postbus 30.001, 9700 RB Groningen.

Ned Tijdschr Geneeskd ; 150(6): 311-8, 2006 Feb 11.

Article in Nl | MEDLINE | ID: mdl-16503023

Subject(s)

Carcinoma, Medullary/prevention & control; Multiple Endocrine Neoplasia Type 2a/prevention & control; Multiple Endocrine Neoplasia Type 2a/surgery; Proto-Oncogene Proteins c-ret/genetics; Thyroid Neoplasms/prevention & control; Thyroidectomy/methods; Adolescent; Calcitonin; Carcinoma, Medullary/genetics; Carcinoma, Medullary/surgery; Child; Child, Preschool; Disease-Free Survival; Female; Follow-Up Studies; Germ-Line Mutation; Heterozygote; Humans; Infant; Lymph Node Excision; Male; Multiple Endocrine Neoplasia Type 2a/genetics; Retrospective Studies; Thyroid Neoplasms/genetics; Thyroid Neoplasms/surgery; Treatment Outcome

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Database: MEDLINE Main subject: Thyroidectomy / Thyroid Neoplasms / Carcinoma, Medullary / Multiple Endocrine Neoplasia Type 2a / Proto-Oncogene Proteins c-ret Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: Nl Journal: Ned Tijdschr Geneeskd Year: 2006 Type: Article

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