Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy.

Bléry, Mathieu; Tze, Lina; Miosge, Lisa A; Jun, Jesse E; Goodnow, Christopher C

Bléry, Mathieu; Tze, Lina; Miosge, Lisa A; Jun, Jesse E; Goodnow, Christopher C.

Affiliation

Bléry M; John Curtin School of Medical Research, The Australian National University, Canberra ACT 2601, Australia.

J Exp Med ; 203(7): 1773-83, 2006 Jul 10.

Article in En | MEDLINE | ID: mdl-16801401

Subject(s)

B-Lymphocytes/immunology; Cholesterol/physiology; Clonal Anergy/immunology; Membrane Lipids/physiology; NF-kappa B/metabolism; Receptors, Antigen, B-Cell/metabolism; Animals; B-Lymphocytes/metabolism; Clonal Anergy/genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Antigen, B-Cell/genetics; Signal Transduction/genetics

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Full text: 1 Database: MEDLINE Main subject: B-Lymphocytes / Receptors, Antigen, B-Cell / Cholesterol / NF-kappa B / Clonal Anergy / Membrane Lipids Limits: Animals Language: En Journal: J Exp Med Year: 2006 Type: Article Affiliation country: Australia

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