Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.

Kim, Hyungjin; Rafiuddin-Shah, Mubina; Tu, Ho-Chou; Jeffers, John R; Zambetti, Gerard P; Hsieh, James J-D; Cheng, Emily H-Y

Kim, Hyungjin; Rafiuddin-Shah, Mubina; Tu, Ho-Chou; Jeffers, John R; Zambetti, Gerard P; Hsieh, James J-D; Cheng, Emily H-Y.

Affiliation

Kim H; Molecular Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

Nat Cell Biol ; 8(12): 1348-58, 2006 Dec.

Article in En | MEDLINE | ID: mdl-17115033

Subject(s)

Apoptosis; Mitochondria/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Animals; Apoptosis Regulatory Proteins/metabolism; BH3 Interacting Domain Death Agonist Protein/metabolism; Bcl-2-Like Protein 11; Cytochromes c/metabolism; Membrane Proteins/metabolism; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins/metabolism; Proto-Oncogene Proteins/metabolism; Tumor Suppressor Proteins/metabolism; bcl-2 Homologous Antagonist-Killer Protein/metabolism; bcl-2-Associated X Protein/metabolism; bcl-X Protein/metabolism

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Database: MEDLINE Main subject: Apoptosis / Proto-Oncogene Proteins c-bcl-2 / Mitochondria Limits: Animals Language: En Journal: Nat Cell Biol Year: 2006 Type: Article Affiliation country: United States

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