Lack of mutagenicity and clastogenicity of PNAEmu-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma.

Boffa, L C; Menichini, P; Bolognesi, C; Cutrona, G; Roncella, S; Damonte, G L; Millo, E; Mariani, M R; Matis, S; Russo, D; Ciliutti, P; Ferrarini, M

Boffa, L C; Menichini, P; Bolognesi, C; Cutrona, G; Roncella, S; Damonte, G L; Millo, E; Mariani, M R; Matis, S; Russo, D; Ciliutti, P; Ferrarini, M.

Affiliation

Boffa LC; Medical Oncology C, National Cancer Research Institute, IST, [corrected] L. go R. Benzi 10, 16132 Genova, Italy. lidia.boffa@istge.it

Mutat Res ; 628(2): 129-37, 2007 Apr 02.

Article in En | MEDLINE | ID: mdl-17267263

Subject(s)

Burkitt Lymphoma/genetics; Enhancer Elements, Genetic; Immunoglobulin mu-Chains/toxicity; Mutagens/toxicity; Nuclear Localization Signals/toxicity; Peptide Nucleic Acids/toxicity; Proto-Oncogene Proteins c-myc/antagonists & inhibitors; Animals; CHO Cells; Cricetinae; Cricetulus; Escherichia coli; Humans; Hypoxanthine Phosphoribosyltransferase/genetics; Lymphocytes/drug effects; Micronucleus Tests; Protein Transport; Proto-Oncogene Proteins c-myc/genetics; Proto-Oncogene Proteins c-myc/metabolism; Salmonella typhimurium

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Database: MEDLINE Main subject: Proto-Oncogene Proteins c-myc / Burkitt Lymphoma / Enhancer Elements, Genetic / Immunoglobulin mu-Chains / Nuclear Localization Signals / Peptide Nucleic Acids / Mutagens Type of study: Evaluation_studies Limits: Animals / Humans Language: En Journal: Mutat Res Year: 2007 Type: Article Affiliation country: Italy

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