Interleukin-1 Receptor-Associated Kinases/metabolism; Membrane Glycoproteins/metabolism; Multiprotein Complexes/metabolism; Protein Processing, Post-Translational/physiology; Receptors, Interleukin-1/metabolism; Signal Transduction/physiology; Toll-Like Receptor 7/metabolism; Animals; Cell Line; Embryo, Mammalian/cytology; Embryo, Mammalian/metabolism; Fibroblasts/cytology; Fibroblasts/metabolism; Inflammation/genetics; Inflammation/metabolism; Interleukin-1 Receptor-Associated Kinases/deficiency; Macrophages/cytology; Macrophages/metabolism; Membrane Glycoproteins/agonists; Membrane Glycoproteins/genetics; Mice; Mice, Inbred BALB C; Mice, Knockout; Multiprotein Complexes/genetics; Mutation; Phosphorylation; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Receptors, Interleukin-1/agonists; Receptors, Interleukin-1/genetics; Toll-Like Receptor 7/agonists; Toll-Like Receptor 7/genetics