Genetic deletion of JNK1 and JNK2 aggravates the DSS-induced colitis in mice.

Chromik, A M; Müller, A M; Körner, J; Belyaev, O; Holland-Letz, T; Schmitz, F; Herdegen, T; Uhl, W; Mittelkötter, U

Chromik, A M; Müller, A M; Körner, J; Belyaev, O; Holland-Letz, T; Schmitz, F; Herdegen, T; Uhl, W; Mittelkötter, U.

Affiliation

Chromik AM; Department of General and Visceral Surgery, St. Josef Hospital, Ruhr-University of Bochum, Bochum, Germany. a.chromik@klinikum-bochum.de

J Invest Surg ; 20(1): 23-33, 2007.

Article in En | MEDLINE | ID: mdl-17365404

Subject(s)

Colitis/enzymology; Mitogen-Activated Protein Kinase 8/physiology; Mitogen-Activated Protein Kinase 9/physiology; Animals; Apoptosis; Chronic Disease; Colitis/chemically induced; Colitis/complications; Colitis/immunology; Colitis/pathology; Crosses, Genetic; Dextran Sulfate/toxicity; Gastrointestinal Hemorrhage/etiology; Intestinal Mucosa/pathology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 8/deficiency; Mitogen-Activated Protein Kinase 8/genetics; Mitogen-Activated Protein Kinase 9/deficiency; Mitogen-Activated Protein Kinase 9/genetics; Single-Blind Method; Weight Loss

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Database: MEDLINE Main subject: Colitis / Mitogen-Activated Protein Kinase 8 / Mitogen-Activated Protein Kinase 9 Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Invest Surg Year: 2007 Type: Article Affiliation country: Germany

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