Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts.

Peterson, Luke F; Boyapati, Anita; Ahn, Eun-Young; Biggs, Joseph R; Okumura, Akiko Joo; Lo, Miao-Chia; Yan, Ming; Zhang, Dong-Er

Peterson, Luke F; Boyapati, Anita; Ahn, Eun-Young; Biggs, Joseph R; Okumura, Akiko Joo; Lo, Miao-Chia; Yan, Ming; Zhang, Dong-Er.

Affiliation

Peterson LF; Department of Molecular and Experimental Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Blood ; 110(3): 799-805, 2007 Aug 01.

Article in En | MEDLINE | ID: mdl-17412887

Subject(s)

Cell Transformation, Neoplastic/genetics; Chromosomes, Human, Pair 21/genetics; Chromosomes, Human, Pair 8/genetics; Core Binding Factor Alpha 2 Subunit/genetics; Leukemia, Myeloid, Acute/genetics; Oncogene Proteins, Fusion/genetics; Translocation, Genetic; Animals; Cell Transformation, Neoplastic/metabolism; Chromosomes, Human, Pair 21/metabolism; Chromosomes, Human, Pair 8/metabolism; Core Binding Factor Alpha 2 Subunit/biosynthesis; Humans; Leukemia, Myeloid, Acute/metabolism; Leukemia, Myeloid, Acute/pathology; Mice; Oncogene Proteins, Fusion/biosynthesis; RUNX1 Translocation Partner 1 Protein; Transcription, Genetic

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Full text: 1 Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 8 / Chromosomes, Human, Pair 21 / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Cell Transformation, Neoplastic / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2007 Type: Article Affiliation country: United States

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