SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes.

Berdeaux, Rebecca; Goebel, Naomi; Banaszynski, Laura; Takemori, Hiroshi; Wandless, Thomas; Shelton, G Diane; Montminy, Marc

Berdeaux, Rebecca; Goebel, Naomi; Banaszynski, Laura; Takemori, Hiroshi; Wandless, Thomas; Shelton, G Diane; Montminy, Marc.

Affiliation

Berdeaux R; Peptide Biology Laboratories, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

Nat Med ; 13(5): 597-603, 2007 May.

Article in En | MEDLINE | ID: mdl-17468767

Subject(s)

Cell Survival/physiology; Histone Deacetylases/metabolism; Muscle Cells/cytology; Muscle, Skeletal/cytology; Muscle, Skeletal/physiology; Protein Serine-Threonine Kinases/metabolism; Repressor Proteins/metabolism; Animals; Calcium/metabolism; Cyclic AMP Response Element-Binding Protein/genetics; Exercise/physiology; Gene Expression Regulation; Histone Deacetylase 2; Humans; MEF2 Transcription Factors; Mice; Mice, Transgenic; Motor Neurons/physiology; Muscular Dystrophy, Animal/genetics; Myogenic Regulatory Factors/metabolism; Protein Serine-Threonine Kinases/deficiency

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Database: MEDLINE Main subject: Repressor Proteins / Cell Survival / Protein Serine-Threonine Kinases / Muscle, Skeletal / Muscle Cells / Histone Deacetylases Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2007 Type: Article Affiliation country: United States

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