Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

Morgan-Lappe, Susan E; Tucker, Lora A; Huang, Xiaoli; Zhang, Qian; Sarthy, Aparna V; Zakula, Dorothy; Vernetti, Lawrence; Schurdak, Mark; Wang, Jieyi; Fesik, Stephen W

Morgan-Lappe, Susan E; Tucker, Lora A; Huang, Xiaoli; Zhang, Qian; Sarthy, Aparna V; Zakula, Dorothy; Vernetti, Lawrence; Schurdak, Mark; Wang, Jieyi; Fesik, Stephen W.

Affiliation

Morgan-Lappe SE; Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA. susan.morgan-lappe@abbott.com

Cancer Res ; 67(9): 4390-8, 2007 May 01.

Article in En | MEDLINE | ID: mdl-17483353

Subject(s)

Cell Cycle Proteins/genetics; Microtubule-Associated Proteins/genetics; Neoplasm Proteins/genetics; Neoplasms/genetics; Nuclear Proteins/genetics; Phosphoproteins/genetics; RNA, Small Interfering/genetics; Stearoyl-CoA Desaturase/genetics; Xenopus Proteins/genetics; ran GTP-Binding Protein/genetics; Cell Cycle/genetics; Cell Death/genetics; Cell Line, Tumor; Cell Survival/genetics; Gene Library; Genes, ras; Humans; Neoplasms/pathology; RNA Interference

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Phosphoproteins / Stearoyl-CoA Desaturase / Nuclear Proteins / Cell Cycle Proteins / Ran GTP-Binding Protein / Xenopus Proteins / RNA, Small Interfering / Microtubule-Associated Proteins / Neoplasm Proteins / Neoplasms Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Cancer Res Year: 2007 Type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links