Impaired mitochondrial Ca2+ homeostasis in respiratory chain-deficient cells but efficient compensation of energetic disadvantage by enhanced anaerobic glycolysis due to low ATP steady state levels.

von Kleist-Retzow, Jürgen-Christoph; Hornig-Do, Hue-Tran; Schauen, Matthias; Eckertz, Sabrina; Dinh, Tuan Anh Duong; Stassen, Frank; Lottmann, Nadine; Bust, Maria; Galunska, Bistra; Wielckens, Klaus; Hein, Wolfgang; Beuth, Joseph; Braun, Jan-Matthias; Fischer, Jürgen H; Ganitkevich, Vladimir Y; Maniura-Weber, Katharina; Wiesner, Rudolf J

von Kleist-Retzow, Jürgen-Christoph; Hornig-Do, Hue-Tran; Schauen, Matthias; Eckertz, Sabrina; Dinh, Tuan Anh Duong; Stassen, Frank; Lottmann, Nadine; Bust, Maria; Galunska, Bistra; Wielckens, Klaus; Hein, Wolfgang; Beuth, Joseph; Braun, Jan-Matthias; Fischer, Jürgen H; Ganitkevich, Vladimir Y; Maniura-Weber, Katharina; Wiesner, Rudolf J.

Affiliation

von Kleist-Retzow JC; Institute of Vegetative Physiology, University of Köln, Robert-Koch-Strasse 39, 50931 Köln, Germany. juergen-christoph.vonkleist@uk-koeln.de

Exp Cell Res ; 313(14): 3076-89, 2007 Aug 15.

Article in En | MEDLINE | ID: mdl-17509565

Subject(s)

Adenosine Triphosphate/metabolism; Calcium/metabolism; Electron Transport/physiology; Glycolysis/physiology; Mitochondria/metabolism; Amino Acids/metabolism; Antioxidants/metabolism; Cell Line; Homeostasis; Humans; Hydrogen-Ion Concentration; Lactic Acid/metabolism; Membrane Potentials/physiology; Oxidation-Reduction; Oxidative Stress; Phenotype; Reactive Oxygen Species/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Adenosine Triphosphate / Calcium / Electron Transport / Glycolysis / Mitochondria Limits: Humans Language: En Journal: Exp Cell Res Year: 2007 Type: Article Affiliation country: Germany

Search on Google

Add to My VHL

XML

PubMed Links