Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease.

Carlsson, Thomas; Carta, Manolo; Winkler, Christian; Björklund, Anders; Kirik, Deniz

Carlsson, Thomas; Carta, Manolo; Winkler, Christian; Björklund, Anders; Kirik, Deniz.

Affiliation

Carlsson T; CNS Disease Modeling Unit, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.

J Neurosci ; 27(30): 8011-22, 2007 Jul 25.

Article in En | MEDLINE | ID: mdl-17652591

Subject(s)

Dyskinesia, Drug-Induced/surgery; Levodopa/adverse effects; Neurons/transplantation; Parkinson Disease/surgery; Serotonin/adverse effects; Animals; Brain Tissue Transplantation/adverse effects; Disease Models, Animal; Dyskinesia, Drug-Induced/physiopathology; Female; Fetal Tissue Transplantation/adverse effects; Neurons/physiology; Parkinson Disease/drug therapy; Parkinson Disease/physiopathology; Rats; Rats, Sprague-Dawley; Serotonin/therapeutic use

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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Levodopa / Serotonin / Dyskinesia, Drug-Induced / Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurosci Year: 2007 Type: Article Affiliation country: Sweden

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