Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri, Angelo; Sanna, Serena; Chen, Wei-Min; Uda, Manuela; Albai, Giuseppe; Strait, James; Najjar, Samer; Nagaraja, Ramaiah; Orrú, Marco; Usala, Gianluca; Dei, Mariano; Lai, Sandra; Maschio, Andrea; Busonero, Fabio; Mulas, Antonella; Ehret, Georg B; Fink, Ashley A; Weder, Alan B; Cooper, Richard S; Galan, Pilar; Chakravarti, Aravinda; Schlessinger, David; Cao, Antonio; Lakatta, Edward; Abecasis, Gonçalo R

Scuteri, Angelo; Sanna, Serena; Chen, Wei-Min; Uda, Manuela; Albai, Giuseppe; Strait, James; Najjar, Samer; Nagaraja, Ramaiah; Orrú, Marco; Usala, Gianluca; Dei, Mariano; Lai, Sandra; Maschio, Andrea; Busonero, Fabio; Mulas, Antonella; Ehret, Georg B; Fink, Ashley A; Weder, Alan B; Cooper, Richard S; Galan, Pilar; Chakravarti, Aravinda; Schlessinger, David; Cao, Antonio; Lakatta, Edward; Abecasis, Gonçalo R.

Affiliation

Scuteri A; Unità Operativa Geriatria, Istituto per la Patologia Endocrina e Metabolica, Rome, Italy.

PLoS Genet ; 3(7): e115, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17658951

Subject(s)

Obesity/genetics; Proteins/genetics; Adiposity/genetics; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Body Weight/genetics; Female; Genetic Predisposition to Disease; Genetic Variation; Genome, Human; Humans; Linkage Disequilibrium; Male; Middle Aged; Obesity/pathology; Phosphofructokinases/genetics; Polymorphism, Single Nucleotide; Quantitative Trait Loci

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Full text: 1 Database: MEDLINE Main subject: Proteins / Obesity Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2007 Type: Article Affiliation country: Italy

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