Peroxisome proliferator-activated receptor-alpha is required for the neurotrophic effect of oleic acid in neurons.

Bento-Abreu, André; Tabernero, Arantxa; Medina, José M

Bento-Abreu, André; Tabernero, Arantxa; Medina, José M.

Affiliation

Bento-Abreu A; Departamento de Bioquímica y Biología Molecular, INCYL, Universidad de Salamanca, Spain.

J Neurochem ; 103(3): 871-81, 2007 Nov.

Article in En | MEDLINE | ID: mdl-17683485

Subject(s)

Cell Differentiation/physiology; Central Nervous System/embryology; Central Nervous System/metabolism; Nerve Growth Factors/metabolism; Neurons/metabolism; Oleic Acid/metabolism; PPAR alpha/metabolism; Animals; Butyrates/pharmacology; Cell Differentiation/drug effects; Cell Shape/drug effects; Cell Shape/physiology; Cells, Cultured; Central Nervous System/cytology; GAP-43 Protein/drug effects; GAP-43 Protein/metabolism; Growth Cones/drug effects; Growth Cones/metabolism; Microtubule-Associated Proteins/drug effects; Microtubule-Associated Proteins/metabolism; Nerve Growth Factors/pharmacology; Neurites/drug effects; Neurites/metabolism; Neurons/cytology; Neurons/drug effects; Oleic Acid/pharmacology; PPAR alpha/agonists; PPAR alpha/genetics; Phenylurea Compounds/pharmacology; Pyrimidines/pharmacology; RNA, Small Interfering/genetics; Rats; Rats, Wistar

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Database: MEDLINE Main subject: Cell Differentiation / Central Nervous System / Oleic Acid / PPAR alpha / Nerve Growth Factors / Neurons Limits: Animals Language: En Journal: J Neurochem Year: 2007 Type: Article Affiliation country: Spain

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