Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel.

Halevy, Sima; Ghislain, Pierre-Dominique; Mockenhaupt, Maja; Fagot, Jean-Paul; Bouwes Bavinck, Jan Nico; Sidoroff, Alexis; Naldi, Luigi; Dunant, Ariane; Viboud, Cecile; Roujeau, Jean-Claude

Halevy, Sima; Ghislain, Pierre-Dominique; Mockenhaupt, Maja; Fagot, Jean-Paul; Bouwes Bavinck, Jan Nico; Sidoroff, Alexis; Naldi, Luigi; Dunant, Ariane; Viboud, Cecile; Roujeau, Jean-Claude.

Affiliation

Halevy S; Department of Dermatology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel. halevy@bgu.ac.il

J Am Acad Dermatol ; 58(1): 25-32, 2008 Jan.

Article in En | MEDLINE | ID: mdl-17919772

Subject(s)

Allopurinol/adverse effects; Gout Suppressants/adverse effects; Stevens-Johnson Syndrome/chemically induced; Stevens-Johnson Syndrome/etiology; Adult; Aged; Allopurinol/administration & dosage; Allopurinol/therapeutic use; Case-Control Studies; Demography; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Europe/epidemiology; Female; Gout Suppressants/administration & dosage; Gout Suppressants/therapeutic use; Humans; Incidence; Israel/epidemiology; Male; Middle Aged; Population Surveillance; Stevens-Johnson Syndrome/epidemiology

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Database: MEDLINE Main subject: Allopurinol / Gout Suppressants / Stevens-Johnson Syndrome Type of study: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia / Europa Language: En Journal: J Am Acad Dermatol Year: 2008 Type: Article Affiliation country: Israel

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