Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn.

Tzika, A Aria; Mintzopoulos, Dionyssios; Padfield, Katie; Wilhelmy, Julie; Mindrinos, Michael N; Yu, Hongue; Cao, Haihui; Zhang, Qunhao; Astrakas, Loukas G; Zhang, Jiangwen; Yu, Yong-Ming; Rahme, Laurence G; Tompkins, Ronald G

Tzika, A Aria; Mintzopoulos, Dionyssios; Padfield, Katie; Wilhelmy, Julie; Mindrinos, Michael N; Yu, Hongue; Cao, Haihui; Zhang, Qunhao; Astrakas, Loukas G; Zhang, Jiangwen; Yu, Yong-Ming; Rahme, Laurence G; Tompkins, Ronald G.

Affiliation

Tzika AA; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. atzika@partners.org

Int J Mol Med ; 21(2): 201-8, 2008 Feb.

Article in En | MEDLINE | ID: mdl-18204786

Subject(s)

Adenosine Triphosphate/biosynthesis; Burns/metabolism; Down-Regulation/genetics; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Trans-Activators/genetics; Animals; Body Surface Area; Burns/genetics; Gene Expression Profiling; Gene Expression Regulation; Magnetic Resonance Spectroscopy; Male; Mice; Models, Biological; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorus Isotopes; RNA, Messenger/genetics; RNA, Messenger/metabolism; Trans-Activators/metabolism; Transcription Factors

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Database: MEDLINE Main subject: Burns / Down-Regulation / Trans-Activators / Adenosine Triphosphate / Muscle, Skeletal Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2008 Type: Article Affiliation country: United States

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