Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury.

Cyrus, Tillmann; Zhang, Huiying; Allen, John S; Williams, Todd A; Hu, Grace; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M

Cyrus, Tillmann; Zhang, Huiying; Allen, John S; Williams, Todd A; Hu, Grace; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M.

Affiliation

Cyrus T; Division of Cardiology, Washington University School of Medicine, Saint Louis, Mo. 63108, USA. tcyrus@im.wustl.edu

Arterioscler Thromb Vasc Biol ; 28(5): 820-6, 2008 May.

Article in En | MEDLINE | ID: mdl-18292395

Subject(s)

Angioplasty, Balloon/adverse effects; Anti-Bacterial Agents/administration & dosage; Constriction, Pathologic/prevention & control; Integrin alphaVbeta3/administration & dosage; Nanoparticles/therapeutic use; Sirolimus/administration & dosage; Animals; Anti-Bacterial Agents/pharmacology; Constriction, Pathologic/drug therapy; Constriction, Pathologic/pathology; Drug-Eluting Stents; Endothelium, Vascular/drug effects; Endothelium, Vascular/pathology; Femoral Artery/drug effects; Femoral Artery/pathology; Magnetic Resonance Imaging; Male; Nanomedicine/methods; Nanoparticles/administration & dosage; Rabbits; Sirolimus/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Angioplasty, Balloon / Constriction, Pathologic / Sirolimus / Integrin alphaVbeta3 / Nanoparticles / Anti-Bacterial Agents Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2008 Type: Article Affiliation country: United States

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