Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.

Atkinson, Helen C; Wood, Susan A; Castrique, Emma S; Kershaw, Yvonne M; Wiles, Crispin C R; Lightman, Stafford L

Atkinson, Helen C; Wood, Susan A; Castrique, Emma S; Kershaw, Yvonne M; Wiles, Crispin C R; Lightman, Stafford L.

Affiliation

Atkinson HC; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK. helena@graduate.uwa.edu.au

Am J Physiol Endocrinol Metab ; 294(6): E1011-22, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18349112

Subject(s)

Adrenal Cortex Hormones/pharmacology; Hypothalamo-Hypophyseal System/metabolism; Pituitary-Adrenal System/metabolism; Receptors, Glucocorticoid/metabolism; Receptors, Mineralocorticoid/metabolism; Adrenal Cortex Hormones/antagonists & inhibitors; Adrenal Cortex Hormones/metabolism; Adrenocorticotropic Hormone/blood; Animals; Area Under Curve; Canrenoic Acid/pharmacology; Corticosterone/blood; Feedback/physiology; Female; Hormone Antagonists/pharmacology; Hypothalamo-Hypophyseal System/drug effects; Methylprednisolone Hemisuccinate/pharmacology; Mifepristone/pharmacology; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System/drug effects; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid/antagonists & inhibitors

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Full text: 1 Database: MEDLINE Main subject: Pituitary-Adrenal System / Receptors, Glucocorticoid / Adrenal Cortex Hormones / Receptors, Mineralocorticoid / Hypothalamo-Hypophyseal System Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2008 Type: Article Affiliation country: United kingdom

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