Involvement of insula and cingulate cortices in control and suppression of natural urges.
Cereb Cortex
; 19(1): 218-23, 2009 Jan.
Article
in En
| MEDLINE
| ID: mdl-18469316
ABSTRACT
The physiology of control and suppression of natural urges is not well understood. We used [(15)O]H(2)O positron-emission tomography imaging to identify neural circuits involved in suppression of spontaneous blinking as a model of normal urges. Suppression of blinking was associated with prominent activation of bilateral insular-claustrum regions, right more than left; activation was also found in bilateral anterior cingulate cortex (ACC), supplementary motor areas, and the face area of the primary motor cortex bilaterally. These results suggest a central role for the insula possibly together with ACC in suppression of blinking.
Full text:
1
Database:
MEDLINE
Main subject:
Blinking
/
Cerebral Cortex
/
Drive
/
Gyrus Cinguli
/
Inhibition, Psychological
/
Motivation
/
Neural Inhibition
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Cereb Cortex
Journal subject:
CEREBRO
Year:
2009
Type:
Article
Affiliation country:
United States