Noncytotoxic Clostridium perfringens enterotoxin (CPE) variants localize CPE intestinal binding and demonstrate a relationship between CPE-induced cytotoxicity and enterotoxicity.

Smedley, James G; Saputo, Juliann; Parker, Jacquelyn C; Fernandez-Miyakawa, Mariano E; Robertson, Susan L; McClane, Bruce A; Uzal, Francisco A

Smedley, James G; Saputo, Juliann; Parker, Jacquelyn C; Fernandez-Miyakawa, Mariano E; Robertson, Susan L; McClane, Bruce A; Uzal, Francisco A.

Affiliation

Smedley JG; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

Infect Immun ; 76(8): 3793-800, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18505809

Subject(s)

Clostridium perfringens/pathogenicity; Enterotoxins/metabolism; Enterotoxins/toxicity; Animals; Cell Survival; Claudin-4; Clostridium perfringens/genetics; Edema/chemically induced; Enterotoxins/genetics; Female; Hemorrhage/chemically induced; Ileum/pathology; Intestinal Mucosa/chemistry; Intestinal Mucosa/pathology; Male; Membrane Proteins/analysis; Necrosis/chemically induced; Protein Binding; Rabbits

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Clostridium perfringens / Enterotoxins Limits: Animals Language: En Journal: Infect Immun Year: 2008 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google