Antitumoral effect of phenazine N5,N10-dioxide derivatives on Caco-2 cells.

Pachón, Olga Gisela; Azqueta, Amaia; Lavaggi, Maria Laura; López de Cerain, Adela; Creppy, Edmond; Collins, Andrew; Cerecetto, Hugo; González, Mercedes; Centelles, Josep Joan; Cascante, Marta

Pachón, Olga Gisela; Azqueta, Amaia; Lavaggi, Maria Laura; López de Cerain, Adela; Creppy, Edmond; Collins, Andrew; Cerecetto, Hugo; González, Mercedes; Centelles, Josep Joan; Cascante, Marta.

Affiliation

Pachón OG; Department of Biochemistry and Molecular Biology, Faculty of Biology, Universitat de Barcelona, Av. Diagonal 645, 08028 Barcelona, Spain.

Chem Res Toxicol ; 21(8): 1578-85, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18553946

Subject(s)

Antineoplastic Agents/pharmacology; Caco-2 Cells/drug effects; Phenazines/pharmacology; Caco-2 Cells/metabolism; Caco-2 Cells/pathology; Caspases/biosynthesis; Cell Cycle/drug effects; Comet Assay; Cytochromes c/biosynthesis; DNA Damage; Drug Screening Assays, Antitumor; Formazans/metabolism; Humans; Molecular Structure; Phenazines/chemistry; Structure-Activity Relationship; Tetrazolium Salts/metabolism

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Full text: 1 Database: MEDLINE Main subject: Phenazines / Caco-2 Cells / Antineoplastic Agents Limits: Humans Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2008 Type: Article Affiliation country: Spain

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