Inhibition of human CYP3A4, UGT1A6, and P-glycoprotein with halogenated xanthene food dyes and prevention by superoxide dismutase.

Furumiya, Kenji; Mizutani, Takaharu

Furumiya, Kenji; Mizutani, Takaharu.

Affiliation

Furumiya K; Department of Drug Metabolism and Disposition, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.

J Toxicol Environ Health A ; 71(19): 1307-13, 2008.

Article in En | MEDLINE | ID: mdl-18686201

Subject(s)

Food Coloring Agents/adverse effects; Hydrocarbons, Halogenated/adverse effects; Microsomes, Liver/drug effects; Xanthenes/adverse effects; ATP Binding Cassette Transporter, Subfamily B, Member 1/drug effects; Cytochrome P-450 CYP3A/drug effects; Glucuronosyltransferase/drug effects; Humans; Superoxide Dismutase/physiology; Xenobiotics/adverse effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Xanthenes / Microsomes, Liver / Food Coloring Agents / Hydrocarbons, Halogenated Limits: Humans Language: En Journal: J Toxicol Environ Health A Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2008 Type: Article Affiliation country: Japan

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google