Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP.

Turcotte, Marc; Tang, Wei; Ross, Elliott M

Turcotte, Marc; Tang, Wei; Ross, Elliott M.

Affiliation

Turcotte M; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

PLoS Comput Biol ; 4(8): e1000148, 2008 Aug 15.

Article in En | MEDLINE | ID: mdl-18716678

Subject(s)

GTP-Binding Proteins/metabolism; GTPase-Activating Proteins/metabolism; Receptors, G-Protein-Coupled/metabolism; Signal Transduction; Binding, Competitive; Enzyme Activation/physiology; Enzyme Inhibitors/metabolism; GTP-Binding Proteins/chemistry; Guanosine Diphosphate/metabolism; Guanosine Triphosphate/metabolism; Hydrolysis; Kinetics; Least-Squares Analysis; Models, Biological; Phospholipase C beta/metabolism; Protein Binding/physiology; Systems Biology/methods; Unilamellar Liposomes; Up-Regulation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Signal Transduction / GTP-Binding Proteins / GTPase-Activating Proteins / Receptors, G-Protein-Coupled Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2008 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google