Anti-GM2 gangliosides IgM paraprotein induces neuromuscular block without neuromuscular damage.

Santafé, Manel M; Sabaté, M Mar; Garcia, Neus; Ortiz, Nico; Lanuza, M Angel; Tomàs, Josep

Santafé, Manel M; Sabaté, M Mar; Garcia, Neus; Ortiz, Nico; Lanuza, M Angel; Tomàs, Josep.

Affiliation

Santafé MM; Unitat d'Histologia i Neurobiologia (UHN), Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, carrer St. Llorenç num 21, 43201-Reus, Spain. msm@fmcs.urv.es

J Neuroimmunol ; 204(1-2): 20-8, 2008 Nov 15.

Article in En | MEDLINE | ID: mdl-18817985

Subject(s)

Gangliosidoses, GM2/immunology; Immunoglobulin M/pharmacology; Neuromuscular Junction/drug effects; Paraproteins/immunology; Analysis of Variance; Animals; Bungarotoxins/metabolism; Chromatography, Thin Layer/methods; Complement System Proteins/metabolism; Demyelinating Diseases/blood; Demyelinating Diseases/immunology; Enzyme-Linked Immunosorbent Assay/methods; Epitopes/immunology; Epitopes/metabolism; Gangliosidoses, GM2/metabolism; Humans; Mice; Microscopy, Electron, Scanning/methods; Miniature Postsynaptic Potentials/drug effects; Miniature Postsynaptic Potentials/physiology; Neuromuscular Blockade; Neuromuscular Junction/metabolism; Neuromuscular Junction/physiology; Neuromuscular Junction/ultrastructure; Paraproteins/metabolism; Qa-SNARE Proteins/metabolism; S100 Proteins/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Immunoglobulin M / Paraproteins / Gangliosidoses, GM2 / Neuromuscular Junction Limits: Animals / Humans Language: En Journal: J Neuroimmunol Year: 2008 Type: Article Affiliation country: Spain

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google