Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment.

Vincent, Thierry; Saikali, Philippe; Cayrol, Romain; Roth, Alejandro D; Bar-Or, Amit; Prat, Alexandre; Antel, Jack P

Vincent, Thierry; Saikali, Philippe; Cayrol, Romain; Roth, Alejandro D; Bar-Or, Amit; Prat, Alexandre; Antel, Jack P.

Affiliation

Vincent T; Laboratoire d'Immunologie, Hôpital Saint-Eloi-CHU Montpellier, Montpellier, France.

J Immunol ; 181(8): 5730-7, 2008 Oct 15.

Article in En | MEDLINE | ID: mdl-18832732

Subject(s)

Aquaporin 4/immunology; Astrocytes/immunology; Autoantibodies/immunology; Blood-Brain Barrier/immunology; Granulocytes/immunology; Immunoglobulin G/immunology; Neuromyelitis Optica/immunology; Adult; Aged; Aged, 80 and over; Animals; Astrocytes/pathology; Autoantibodies/blood; Blood-Brain Barrier/pathology; Cell Degranulation/immunology; Cerebellum/blood supply; Cerebellum/immunology; Cerebellum/pathology; Complement System Proteins/immunology; Female; Fetus/immunology; Fetus/pathology; Granulocytes/pathology; Humans; Immunity, Cellular/immunology; Immunoglobulin G/blood; Killer Cells, Natural/immunology; Killer Cells, Natural/pathology; Male; Middle Aged; Multiple Sclerosis/blood; Multiple Sclerosis/immunology; Multiple Sclerosis/pathology; Neuromyelitis Optica/blood; Neuromyelitis Optica/pathology; Permeability; Primates

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Database: MEDLINE Main subject: Autoantibodies / Immunoglobulin G / Blood-Brain Barrier / Astrocytes / Neuromyelitis Optica / Aquaporin 4 / Granulocytes Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Immunol Year: 2008 Type: Article Affiliation country: France

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