Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

Bertram, Lars; Lange, Christoph; Mullin, Kristina; Parkinson, Michele; Hsiao, Monica; Hogan, Meghan F; Schjeide, Brit M M; Hooli, Basavaraj; Divito, Jason; Ionita, Iuliana; Jiang, Hongyu; Laird, Nan; Moscarillo, Thomas; Ohlsen, Kari L; Elliott, Kathryn; Wang, Xin; Hu-Lince, Diane; Ryder, Marie; Murphy, Amy; Wagner, Steven L; Blacker, Deborah; Becker, K David; Tanzi, Rudolph E

Bertram, Lars; Lange, Christoph; Mullin, Kristina; Parkinson, Michele; Hsiao, Monica; Hogan, Meghan F; Schjeide, Brit M M; Hooli, Basavaraj; Divito, Jason; Ionita, Iuliana; Jiang, Hongyu; Laird, Nan; Moscarillo, Thomas; Ohlsen, Kari L; Elliott, Kathryn; Wang, Xin; Hu-Lince, Diane; Ryder, Marie; Murphy, Amy; Wagner, Steven L; Blacker, Deborah; Becker, K David; Tanzi, Rudolph E.

Affiliation

Bertram L; Genetics and Aging Research Unit, Mass General Institute for Neurodegenerative Disease (MIND), Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

Am J Hum Genet ; 83(5): 623-32, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18976728

Subject(s)

Alzheimer Disease/genetics; Apolipoproteins E/genetics; Genetic Predisposition to Disease; Genome-Wide Association Study; Age of Onset; Algorithms; Alleles; Bayes Theorem; Case-Control Studies; Chromosomes, Human, Pair 14; Genetic Markers; Humans; Linear Models; Linkage Disequilibrium; Pedigree; Polymorphism, Single Nucleotide; Sialic Acid Binding Ig-like Lectin 3/genetics; White People

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Full text: 1 Database: MEDLINE Main subject: Apolipoproteins E / Genetic Predisposition to Disease / Genome-Wide Association Study / Alzheimer Disease Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Am J Hum Genet Year: 2008 Type: Article Affiliation country: United States

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