AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets.

Gardini, Alessandro; Cesaroni, Matteo; Luzi, Lucilla; Okumura, Akiko J; Biggs, Joseph R; Minardi, Simone P; Venturini, Elisa; Zhang, Dong-Er; Pelicci, Pier Giuseppe; Alcalay, Myriam

Gardini, Alessandro; Cesaroni, Matteo; Luzi, Lucilla; Okumura, Akiko J; Biggs, Joseph R; Minardi, Simone P; Venturini, Elisa; Zhang, Dong-Er; Pelicci, Pier Giuseppe; Alcalay, Myriam.

Affiliation

Gardini A; Department of Experimental Oncology, IEO-European Institute of Oncology, Milan, Italy.

PLoS Genet ; 4(11): e1000275, 2008 Nov.

Article in En | MEDLINE | ID: mdl-19043539

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/metabolism; Core Binding Factor Alpha 2 Subunit/metabolism; Oncogene Proteins, Fusion/genetics; Animals; Binding Sites; Cell Line, Tumor; Chromosomes, Human, Pair 19/genetics; HeLa Cells; Humans; Mice; Oncogene Proteins, Fusion/metabolism; Promoter Regions, Genetic; RUNX1 Translocation Partner 1 Protein; Transcription, Genetic; U937 Cells

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Full text: 1 Database: MEDLINE Main subject: Oncogene Proteins, Fusion / Basic Helix-Loop-Helix Transcription Factors / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2008 Type: Article Affiliation country: Italy

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