Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity.

Brew, Christine T; Aronchik, Ida; Kosco, Karena; McCammon, Jasmine; Bjeldanes, Leonard F; Firestone, Gary L

Brew, Christine T; Aronchik, Ida; Kosco, Karena; McCammon, Jasmine; Bjeldanes, Leonard F; Firestone, Gary L.

Affiliation

Brew CT; Department of Molecular and Cell Biology, The University of California at Berkeley, Berkeley, CA 94720-3200, USA.

Int J Cancer ; 124(10): 2294-302, 2009 May 15.

Article in En | MEDLINE | ID: mdl-19173291

Subject(s)

Cell Adhesion/drug effects; Cell Movement/drug effects; Focal Adhesion Protein-Tyrosine Kinases/metabolism; Indoles/pharmacology; rhoA GTP-Binding Protein/metabolism; Cell Line, Tumor; Enzyme Activation; Fluorescent Antibody Technique; Humans

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Full text: 1 Database: MEDLINE Main subject: Cell Adhesion / Cell Movement / RhoA GTP-Binding Protein / Focal Adhesion Protein-Tyrosine Kinases / Indoles Limits: Humans Language: En Journal: Int J Cancer Year: 2009 Type: Article Affiliation country: United States

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