Single-molecule fluorescence studies reveal long-range electron-transfer dynamics through double-stranded DNA.

ABSTRACT

Complex dynamics of combined long-range fluorescence resonance energy transfer (FRET) and short-range electron transfer (ET) processes in a single double-stranded DNA (dsDNA) molecule (see figure) reveals that FRET remains almost unaltered in the presence of ET. Present systems also demonstrate the potential for long-range ET studies through the base stack in single dsDNA molecules.