Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes.

Nakahara, Makoto; Sonoda, Eiichiro; Nojima, Kuniharu; Sale, Julian E; Takenaka, Katsuya; Kikuchi, Koji; Taniguchi, Yoshihito; Nakamura, Kyoko; Sumitomo, Yoshiki; Bree, Ronan T; Lowndes, Noel F; Takeda, Shunichi

Nakahara, Makoto; Sonoda, Eiichiro; Nojima, Kuniharu; Sale, Julian E; Takenaka, Katsuya; Kikuchi, Koji; Taniguchi, Yoshihito; Nakamura, Kyoko; Sumitomo, Yoshiki; Bree, Ronan T; Lowndes, Noel F; Takeda, Shunichi.

Affiliation

Nakahara M; CREST Research Project, Japan Science and Technology Agency, Saitama, Japan.

PLoS Genet ; 5(1): e1000356, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19180185

Subject(s)

B-Lymphocytes/metabolism; DNA Breaks, Single-Stranded; Immunoglobulin Variable Region/genetics; Nuclear Proteins/metabolism; Recombination, Genetic; Animals; Cell Line, Tumor; Chickens; DNA Repair; Exodeoxyribonucleases/genetics; Exodeoxyribonucleases/metabolism; Gene Conversion; Immunoglobulin Variable Region/metabolism; Nuclear Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Recombination, Genetic / Immunoglobulin Variable Region / Nuclear Proteins / B-Lymphocytes / DNA Breaks, Single-Stranded Limits: Animals Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2009 Type: Article Affiliation country: Japan

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