Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.

Patham, Bhargavi; Duffy, Josh; Lane, Ariel; Davis, Richard C; Wipf, Peter; Fewell, Sheara W; Brodsky, Jeffrey L; Mensa-Wilmot, Kojo

Patham, Bhargavi; Duffy, Josh; Lane, Ariel; Davis, Richard C; Wipf, Peter; Fewell, Sheara W; Brodsky, Jeffrey L; Mensa-Wilmot, Kojo.

Affiliation

Patham B; Department of Cellular Biology, University of Georgia, 724 Biological Sciences Building, Athens, GA 30602, USA.

Biochem J ; 419(2): 507-17, 2009 Apr 15.

Article in En | MEDLINE | ID: mdl-19196237

Subject(s)

Endoplasmic Reticulum/metabolism; Trypanosoma brucei brucei/metabolism; Variant Surface Glycoproteins, Trypanosoma/metabolism; Animals; HeLa Cells; Humans; Naphthalenes/pharmacology; Protein Transport/drug effects; Pyrrolidinones/pharmacology; Rats; Tetrahydronaphthalenes/pharmacology; Variant Surface Glycoproteins, Trypanosoma/genetics

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Full text: 1 Database: MEDLINE Main subject: Trypanosoma brucei brucei / Variant Surface Glycoproteins, Trypanosoma / Endoplasmic Reticulum Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochem J Year: 2009 Type: Article Affiliation country: United States

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