Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

Nicholls, Sarah; Piper, Karen P; Mohammed, Fiyaz; Dafforn, Timothy R; Tenzer, Stefan; Salim, Mahboob; Mahendra, Premini; Craddock, Charles; van Endert, Peter; Schild, Hansjörg; Cobbold, Mark; Engelhard, Victor H; Moss, Paul A H; Willcox, Benjamin E

Nicholls, Sarah; Piper, Karen P; Mohammed, Fiyaz; Dafforn, Timothy R; Tenzer, Stefan; Salim, Mahboob; Mahendra, Premini; Craddock, Charles; van Endert, Peter; Schild, Hansjörg; Cobbold, Mark; Engelhard, Victor H; Moss, Paul A H; Willcox, Benjamin E.

Affiliation

Nicholls S; Cancer Research UK Institute for Cancer Studies, Edgbaston, Birmingham B15 2TT, United Kingdom.

Proc Natl Acad Sci U S A ; 106(10): 3889-94, 2009 Mar 10.

Article in En | MEDLINE | ID: mdl-19234124

Subject(s)

Minor Histocompatibility Antigens/chemistry; Minor Histocompatibility Antigens/genetics; Polymorphism, Genetic; Receptors, Antigen, T-Cell/immunology; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters/metabolism; Arginine/metabolism; Cell Separation; Circular Dichroism; Crystallography, X-Ray; Epitopes/chemistry; Epitopes/immunology; HLA-A2 Antigen/chemistry; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/immunology; Proteasome Endopeptidase Complex/metabolism; Protein Binding; Protein Stability; Protein Structure, Secondary; Protein Transport; Receptors, Antigen, T-Cell/chemistry; Surface Plasmon Resonance; T-Lymphocytes, Cytotoxic/immunology; Tissue Donors

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Polymorphism, Genetic / Receptors, Antigen, T-Cell / Minor Histocompatibility Antigens Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article Affiliation country: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google