Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferator-activated receptors.

Tsuji, Kiyomi; Satoh, Shigeru; Mitsutake, Susumu; Murakami, Itsuo; Park, Jeong-Ju; Li, Qian; Chang, Young-Tae; Chung, Sung-Kee; Igarashi, Yasuyuki

Tsuji, Kiyomi; Satoh, Shigeru; Mitsutake, Susumu; Murakami, Itsuo; Park, Jeong-Ju; Li, Qian; Chang, Young-Tae; Chung, Sung-Kee; Igarashi, Yasuyuki.

Affiliation

Tsuji K; Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Science, Hokkaido University, Nishi 11, Kita 21, Kita-ku, Sapporo 001-0021, Japan.

Bioorg Med Chem Lett ; 19(6): 1643-6, 2009 Mar 15.

Article in En | MEDLINE | ID: mdl-19237283

Subject(s)

Chemistry, Pharmaceutical/methods; Peroxisome Proliferator-Activated Receptors/metabolism; Sphingolipids/chemical synthesis; Animals; Ceramides/chemistry; Drug Design; Genes, Reporter; Ligands; Luciferases/metabolism; Mice; NIH 3T3 Cells; Plasmids/metabolism; Sphingolipids/pharmacology; Transcription, Genetic; Transcriptional Activation

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Full text: 1 Database: MEDLINE Main subject: Sphingolipids / Chemistry, Pharmaceutical / Peroxisome Proliferator-Activated Receptors Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: Japan

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