A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1.

Schmerk, Crystal L; Duplantis, Barry N; Howard, Perry L; Nano, Francis E

Schmerk, Crystal L; Duplantis, Barry N; Howard, Perry L; Nano, Francis E.

Affiliation

Schmerk CL; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Duplantis BN; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Howard PL; Department of Biology, University of Victoria, Victoria, BC, Canada.
Nano FE; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.

Microbiology (Reading) ; 155(Pt 5): 1498-1504, 2009 May.

Article in En | MEDLINE | ID: mdl-19372155

Subject(s)

Bacterial Proteins/genetics; DNA Replication; Francisella/genetics; Gram-Negative Bacterial Infections/metabolism; Lysosomal-Associated Membrane Protein 1/metabolism; Sequence Deletion; Virulence Factors/genetics; Animals; Bacterial Proteins/metabolism; Cell Line; Cells, Cultured; Female; Francisella/metabolism; Francisella/pathogenicity; Gene Expression Regulation, Bacterial; Gram-Negative Bacterial Infections/genetics; Gram-Negative Bacterial Infections/microbiology; Humans; Lysosomal-Associated Membrane Protein 1/genetics; Lysosomes/genetics; Lysosomes/metabolism; Mice; Mice, Inbred BALB C; Protein Binding; Virulence; Virulence Factors/metabolism

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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Gram-Negative Bacterial Infections / Sequence Deletion / Virulence Factors / DNA Replication / Lysosomal-Associated Membrane Protein 1 / Francisella Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Microbiology (Reading) Journal subject: MICROBIOLOGIA Year: 2009 Type: Article Affiliation country: Canada

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