Carcinoma, Non-Small-Cell Lung/genetics; Cell Cycle Proteins/genetics; Chromosomal Instability; Lung Neoplasms/genetics; Oncogene Proteins/genetics; Tumor Suppressor Protein p53/genetics; Aneuploidy; Animals; Antineoplastic Agents, Phytogenic/pharmacology; Carcinoma, Non-Small-Cell Lung/metabolism; Carcinoma, Non-Small-Cell Lung/pathology; Cell Adhesion/physiology; Cell Cycle Proteins/metabolism; Cell Movement/physiology; Cell Proliferation; Cytogenetic Analysis; Drug Synergism; Etoposide/pharmacology; Female; Flow Cytometry; Humans; Immunoblotting; Immunoenzyme Techniques; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Mutagens/pharmacology; Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-raf/genetics; Proto-Oncogene Proteins c-raf/metabolism; Proto-Oncogene Proteins p21(ras)/genetics; Proto-Oncogene Proteins p21(ras)/metabolism; Translocation, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53/metabolism