Effects of lactational exposure to benzo[alpha]pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice.

Bouayed, Jaouad; Desor, Frédéric; Rammal, Hassan; Kiemer, Alexandra K; Tybl, Elisabeth; Schroeder, Henri; Rychen, Guido; Soulimani, Rachid

Bouayed, Jaouad; Desor, Frédéric; Rammal, Hassan; Kiemer, Alexandra K; Tybl, Elisabeth; Schroeder, Henri; Rychen, Guido; Soulimani, Rachid.

Affiliation

Bouayed J; Neurotoxicologie Alimentaire et Bioactivié, UR AFPA, Université Paul Verlaine de Metz-INPL-INRA, BP 4102, 57040 Metz, France. bouayedj@yahoo.fr

Toxicology ; 259(3): 97-106, 2009 May 17.

Article in En | MEDLINE | ID: mdl-19428949

Subject(s)

Behavior, Animal/drug effects; Benzo(a)pyrene/toxicity; Brain/drug effects; Environmental Pollutants/toxicity; Maternal Exposure/adverse effects; Animals; Animals, Newborn; Anxiety/chemically induced; Benzo(a)pyrene/pharmacokinetics; Brain/growth & development; Brain/metabolism; Environmental Pollutants/pharmacokinetics; Female; Lactation; Male; Memory/drug effects; Mice; Motor Activity/drug effects; Random Allocation; Receptors, Adrenergic, alpha-1/biosynthesis; Receptors, Adrenergic, alpha-1/genetics; Receptors, GABA-A/biosynthesis; Receptors, GABA-A/genetics; Receptors, Opioid, mu/biosynthesis; Receptors, Opioid, mu/genetics; Receptors, Serotonin/biosynthesis; Receptors, Serotonin/genetics; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Database: MEDLINE Main subject: Behavior, Animal / Benzo(a)pyrene / Brain / Maternal Exposure / Environmental Pollutants Limits: Animals Language: En Journal: Toxicology Year: 2009 Type: Article Affiliation country: France

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