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AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Rhodes, Daniel R; Ateeq, Bushra; Cao, Qi; Tomlins, Scott A; Mehra, Rohit; Laxman, Bharathi; Kalyana-Sundaram, Shanker; Lonigro, Robert J; Helgeson, Beth E; Bhojani, Mahaveer S; Rehemtulla, Alnawaz; Kleer, Celina G; Hayes, Daniel F; Lucas, Peter C; Varambally, Sooryanarayana; Chinnaiyan, Arul M.
Affiliation
  • Rhodes DR; Michigan Center for Translational Pathology, Howard Hughes Medical Institute, and Departments of Urology, and Pathology, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI 48109-5602.
Proc Natl Acad Sci U S A ; 106(25): 10284-9, 2009 Jun 23.
Article in En | MEDLINE | ID: mdl-19487683
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / Drug Resistance, Neoplasm / Losartan / Receptor, Angiotensin, Type 1 / Angiotensin II Type 1 Receptor Blockers Type of study: Diagnostic_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / Drug Resistance, Neoplasm / Losartan / Receptor, Angiotensin, Type 1 / Angiotensin II Type 1 Receptor Blockers Type of study: Diagnostic_studies Limits: Animals / Female / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article