Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase.

Agarwal, Nisheeth; Lamichhane, Gyanu; Gupta, Radhika; Nolan, Scott; Bishai, William R

Agarwal, Nisheeth; Lamichhane, Gyanu; Gupta, Radhika; Nolan, Scott; Bishai, William R.

Affiliation

Agarwal N; Department of Medicine, Johns Hopkins School of Medicine, CRB2, Room 1.08, 1550 Orleans Street, Baltimore, Maryland 21231-1044, USA.

Nature ; 460(7251): 98-102, 2009 Jul 02.

Article in En | MEDLINE | ID: mdl-19516256

Subject(s)

Adenylyl Cyclases/metabolism; Cyclic AMP/metabolism; Macrophages/metabolism; Macrophages/pathology; Mycobacterium tuberculosis/enzymology; Mycobacterium tuberculosis/pathogenicity; Tuberculosis/pathology; Adenylyl Cyclases/genetics; Animals; Cell Line; Cyclic AMP Response Element-Binding Protein/metabolism; Cyclic AMP-Dependent Protein Kinases/metabolism; Cytosol/metabolism; Cytosol/microbiology; Macrophages/immunology; Macrophages/microbiology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mycobacterium tuberculosis/genetics; Mycobacterium tuberculosis/growth & development; Phosphoric Diester Hydrolases/genetics; Phosphoric Diester Hydrolases/metabolism; Phosphorylation; Tuberculosis/immunology; Tuberculosis/microbiology; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/metabolism; Virulence/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Tuberculosis / Adenylyl Cyclases / Cyclic AMP / Macrophages / Mycobacterium tuberculosis Limits: Animals Language: En Journal: Nature Year: 2009 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google