Brain/metabolism; Epilepsy/etiology; Gene Expression Profiling/methods; Gene Expression/physiology; Signal Transduction/physiology; Transforming Growth Factor beta/metabolism; Action Potentials/physiology; Albumins/metabolism; Animals; Antibodies/pharmacology; Astrocytes/metabolism; Benzamides/pharmacology; Blood-Brain Barrier/drug effects; Brain/physiopathology; Cluster Analysis; Dioxoles/pharmacology; Disease Models, Animal; Electric Stimulation/adverse effects; Epilepsy/complications; Epilepsy/pathology; Gene Expression Regulation; Genome-Wide Association Study/methods; Glutamic Acid/genetics; Glutamic Acid/metabolism; Immunoprecipitation/methods; In Vitro Techniques; Inflammation/etiology; Ion Channels/genetics; Ion Channels/metabolism; Male; Microarray Analysis/methods; Rats; Rats, Wistar; Smad2 Protein/metabolism; Statistics, Nonparametric; Transforming Growth Factor beta/genetics; Transforming Growth Factor beta/immunology; Transforming Growth Factor beta/pharmacology; Transforming Growth Factor beta2/antagonists & inhibitors; Transforming Growth Factor beta2/immunology; Transforming Growth Factor beta2/metabolism; gamma-Aminobutyric Acid/genetics; gamma-Aminobutyric Acid/metabolism