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Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
Kim, Minji; Suh, Jaehong; Romano, Donna; Truong, Mimy H; Mullin, Kristina; Hooli, Basavaraj; Norton, David; Tesco, Giuseppina; Elliott, Kathy; Wagner, Steven L; Moir, Robert D; Becker, K David; Tanzi, Rudolph E.
Affiliation
  • Kim M; MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Hum Mol Genet ; 18(20): 3987-96, 2009 Oct 15.
Article in En | MEDLINE | ID: mdl-19608551
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Full text: 1 Database: MEDLINE Main subject: ADAM Proteins / Amyloid Precursor Protein Secretases / Alzheimer Disease / Membrane Proteins / Mutation Type of study: Risk_factors_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: ADAM Proteins / Amyloid Precursor Protein Secretases / Alzheimer Disease / Membrane Proteins / Mutation Type of study: Risk_factors_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Type: Article Affiliation country: United States