A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).

Terabayashi, Takeshi; Funato, Yosuke; Fukuda, Mitsunori; Miki, Hiroaki

Terabayashi, Takeshi; Funato, Yosuke; Fukuda, Mitsunori; Miki, Hiroaki.

Affiliation

Terabayashi T; Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.

J Biol Chem ; 284(39): 26716-24, 2009 Sep 25.

Article in En | MEDLINE | ID: mdl-19643732

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Frizzled Receptors/metabolism; Lysosomes/metabolism; Phosphoproteins/metabolism; Protein Serine-Threonine Kinases/metabolism; Receptors, G-Protein-Coupled/metabolism; Adaptor Proteins, Signal Transducing/genetics; Animals; Blotting, Western; COS Cells; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Dishevelled Proteins; Endocytosis; Frizzled Receptors/genetics; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Humans; Intracellular Space/metabolism; Mice; Microscopy, Confocal; NIH 3T3 Cells; Phosphoproteins/genetics; Protein Binding; Protein Serine-Threonine Kinases/genetics; RNA, Small Interfering/genetics; Receptors, G-Protein-Coupled/genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Wnt Proteins/metabolism; beta Catenin/metabolism

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Full text: 1 Database: MEDLINE Main subject: Phosphoproteins / Protein Serine-Threonine Kinases / Receptors, G-Protein-Coupled / Adaptor Proteins, Signal Transducing / Frizzled Receptors / Lysosomes Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2009 Type: Article Affiliation country: Japan

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