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GDC-0449-a potent inhibitor of the hedgehog pathway.
Robarge, Kirk D; Brunton, Shirley A; Castanedo, Georgette M; Cui, Yong; Dina, Michael S; Goldsmith, Richard; Gould, Stephen E; Guichert, Oivin; Gunzner, Janet L; Halladay, Jason; Jia, Wei; Khojasteh, Cyrus; Koehler, Michael F T; Kotkow, Karen; La, Hank; Lalonde, Rebecca L; Lau, Kevin; Lee, Leslie; Marshall, Derek; Marsters, James C; Murray, Lesley J; Qian, Changgeng; Rubin, Lee L; Salphati, Laurent; Stanley, Mark S; Stibbard, John H A; Sutherlin, Daniel P; Ubhayaker, Savita; Wang, Shumei; Wong, Susan; Xie, Minli.
Affiliation
  • Robarge KD; Genentech, Small Molecule Drug Discovery 1 DNA Way, South San Francisco, CA 94080, United States. kir@gene.com
Bioorg Med Chem Lett ; 19(19): 5576-81, 2009 Oct 01.
Article in En | MEDLINE | ID: mdl-19716296
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Full text: 1 Database: MEDLINE Main subject: Pyridines / Hedgehog Proteins / Amides / Anilides Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Pyridines / Hedgehog Proteins / Amides / Anilides Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: United States